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IPF    |     ENV-101     |     WHISTLE-PF TRIAL

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Living with Idiopathic Pulmonary Fibrosis (IPF)?

WHISTLE-PF:
A new clinical trial for individuals with pulmonary fibrosis

LEARN MORE ABOUT IPF
Idiopathic Pulmonary Fibrosis

Understanding Idiopathic Pulmonary Fibrosis

IPF is a lung disease that causes abnormal scarring in the lungs, leading to shortness of breath and persistent cough. This disease can worsen over time, making it difficult for the lungs to absorb oxygen and ultimately impacting individuals' quality of life.
 

Current treatments may help slow the progress of IPF in some people, but they do not stop or reverse it. Individuals living with IPF may benefit from new treatment options that go beyond slowing disease progression to reverse lung fibrosis and improve lung function.

Introducing ENV-101

ENV-101 is an oral medicine being investigated by Endeavor BioMedicines, Inc., to treat fibrotic lung diseases, starting with IPF. ENV-101 blocks a protein in the body that is thought to be involved in lung scarring. Endeavor BioMedicines is evaluating whether ENV-101 may slow or reverse the disease and improve the symptoms of IPF.

Clinical Studies to Date
Endeavor BioMedicines recently evaluated ENV-101 in 21 patients with IPF. More information about this study is available at
endeavorbiomedicines.com

The WHISTLE-PF Trial

Endeavor BioMedicines plans to initiate patient enrollment in a global trial designed to further evaluate the therapeutic potential of ENV-101 in individuals with IPF. The WHISTLE-PF clinical trial stands for Wound-remodeling Hedgehog-inhibitor ILD Study Testing Lung Function Endpoints. It is a Phase 2 trial evaluating the safety and efficacy of ENV-101.




Idiopathic Pulmonary Fibrosis

Endeavor BioMedicines:

Disrupting Disease, Restoring Hope

Endeavor BioMedicines is a clinical-stage biotechnology company developing medicines with the potential to deliver transformational clinical benefits to patients with life-threatening diseases.


Endeavor’s lead investigational candidate, ENV-101, is an inhibitor of the Hedgehog (Hh) signaling pathway in clinical development for the treatment of idiopathic pulmonary fibrosis (IPF).

Copyright © Endeavor BioMedicines

Copyright © Endeavor BioMedicines